This brings the number of poachers killed in the Southern Africa country to seven this year.
BDF spokesperson, Col. Tebo Dikole, on Thursday said the incident occurred on May 21 in Okavango Delta.
The two poachers were killed during an exchange of fire with a patrol team.
Dikole said that poachers continue to target endangered species such as rhinos.
The incident comes after authorities in Botswana announced the puzzling death of 56 elephants in the Seronga and Eretsha villages in the North-West of the country, adjacent to the Okavango Delta.
Botswana has seen an unprecedented rise in poaching activities in the last 12 months, according to reports.
AFRICA TODAY NEWS, NEW YORK